Mechanisms of carcinogenic activity triggered by lysine-specific demethylase 1A
Epigenetics has emerged Andrographis as a prime focus area in the field of cancer research.Lysine-specific demethylase 1A (LSD1), the first discovered histone demethylase, is mainly responsible for catalysing demethylation of histone 3 lysine 4 (H3K4) and H3K9 to activate or inhibit gene transcription.LSD1 is abnormally expressed in various cancers